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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNB1
All Species:
20.91
Human Site:
S126
Identified Species:
38.33
UniProt:
P14635
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14635
NP_114172.1
433
48337
S126
P
I
L
V
D
T
A
S
P
S
P
M
E
T
S
Chimpanzee
Pan troglodytes
XP_517728
536
59103
S229
P
I
L
V
D
T
P
S
P
S
P
M
E
T
S
Rhesus Macaque
Macaca mulatta
XP_001091533
433
48375
S126
P
I
L
V
D
T
P
S
P
S
P
M
E
T
S
Dog
Lupus familis
XP_850398
425
47378
S118
P
I
L
V
D
T
P
S
P
S
P
M
E
T
S
Cat
Felis silvestris
Mouse
Mus musculus
P24860
430
48033
S123
P
I
L
V
D
N
P
S
P
S
P
M
E
T
S
Rat
Rattus norvegicus
P30277
423
47373
S116
P
I
L
V
D
T
P
S
P
S
P
M
E
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507609
428
47366
E121
P
P
S
P
S
P
M
E
T
S
G
C
E
V
S
Chicken
Gallus gallus
P29332
399
44633
Q105
V
P
M
D
V
S
M
Q
E
E
D
L
C
Q
A
Frog
Xenopus laevis
P13350
397
44655
D106
E
T
S
G
C
L
P
D
E
L
C
Q
A
F
S
Zebra Danio
Brachydanio rerio
NP_571588
398
44818
D108
T
S
G
C
A
S
D
D
L
C
Q
A
F
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20439
530
59237
V219
L
I
R
G
N
S
A
V
T
T
T
T
S
T
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39071
444
50417
D139
I
R
M
V
E
S
L
D
A
S
A
S
K
Q
K
Baker's Yeast
Sacchar. cerevisiae
P24869
491
56228
E122
S
I
K
E
G
R
A
E
L
P
A
N
I
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.5
98.6
91.2
N.A.
86.3
84.7
N.A.
75.7
50.5
66.2
61.8
N.A.
34.3
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
99.3
94
N.A.
91.9
90.5
N.A.
84.5
66.9
78.2
75.7
N.A.
49.4
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
93.3
N.A.
26.6
0
6.6
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
93.3
N.A.
26.6
26.6
6.6
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.1
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
24
0
8
0
16
8
8
0
8
% A
% Cys:
0
0
0
8
8
0
0
0
0
8
8
8
8
0
0
% C
% Asp:
0
0
0
8
47
0
8
24
0
0
8
0
0
0
8
% D
% Glu:
8
0
0
8
8
0
0
16
16
8
0
0
54
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
0
8
16
8
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
62
0
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% K
% Leu:
8
0
47
0
0
8
8
0
16
8
0
8
0
0
8
% L
% Met:
0
0
16
0
0
0
16
0
0
0
0
47
0
0
8
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
54
16
0
8
0
8
47
0
47
8
47
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
8
0
16
0
% Q
% Arg:
0
8
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
16
0
8
31
0
47
0
62
0
8
8
16
62
% S
% Thr:
8
8
0
0
0
39
0
0
16
8
8
8
0
54
0
% T
% Val:
8
0
0
54
8
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _